EFFECT OF AMORPHOPHALLUSONCOPHYL LUS PRAIN EX. HOOK. F. TUBERS ADMINISTRATION IN PREVENTING METABOLIC SYNDROME
Abstract
Epidemiological studies showed that the prevalence of global metabolic syndrome had increased. The main cause of metabolic syndrome was excessive consumption of carbohydrate. Therefore, the purpose of this study
was to find the alternative source of carbohydrate that could suppress the occurrence of metabolic syndrome. One of the potential plants was Amorphophallusoncophyllus tubers (AOT), because of its high glucomannan
content. This study was performed in in vivo method by using 3 groups of animals, that were administered food without carbohydrates, food with rice as carbohydrate, and AOT as carbohydrate for 42 days. Parameters measured were body weight, HDL and triglyceride level, insulin sensitivity (value of KITT), and blood pressure. The results showed body weight in the control group, rice, and AOT were 250.3 g, 316.4 g, 115.0 g; HDL levels 11.2 mg / dL, 9.6 mg / dL, 16.5 mg / dL; triglyceride levels 31.6 mg / dL, 84.1 mg / dL, 44.9 mg / dL; KITT value 1.58, 0.78, 2.06; and blood pressure 113/77 mmHg, 152/96 mmHg, and 101/75 mmHg; respectively. It could be concluded that the AOT as a source of carbohydrates could prevent the occurrence of metabolic syndrome.